This is the latest edition of the classic book on the subject of multiple sclerosis. An international group of authors has been involved in updating this edition which features more information on imaging and investigations, and a new chapter on neurobiology and glial development.new edition of the classic book on the subject four new authors, all internationally known authorities from UK, Canada, Germany & Austria much more on imaging and investigations than 2E new chapter on neurobiology and glial development much better illustrated than 2E very well referenced totally rewritten, except for chapters 2 & 3 on symptoms and diagnosis, which have been revised