He received a B.A. in Medieval History from Harvard University (1961), and a Ph.D. in Anthropology from the University of Chicago (1966), where he studied under David M. Schneider. He conducted fieldwork among the Daribi of Karimui, in the Simbu Province of Papua New Guinea, as well as the Usen Barok of New Ireland. Wagner taught at Southern Illinois University and Northwestern University before accepting the chairmanship of the Department of Anthropology at the University of Virginia, where he currently teaches.
Specializations Indigenous conceptual systems, especially involving kin relations; ritual, myth and worldview in Melanesia, Australia, and North America; pragmatics of cultural representation (imagery, writing, and speech) as a basis for symbolism; shamanism and curing techniques exclusive of psychological, political, or "ethnic" perspectives; studies involving the human element in technology and power concepts.