Jojo’s answer to “I am just reading Me before you now. I was very curious about Lou's name. It is Louisa Clark. Any c…” > Likes and Comments

My guess is the OP was asking if there is a connection of "Louisa Clark" to this:

http://en.wikipedia.org/wiki/Lewis_an...

or maybe even this:
http://en.wikipedia.org/wiki/Lois_%26...

Or Lewis and Clark?

he means the famous american couple Lous and Clark from Superman's story