Underground Knowledge — A discussion group discussion

Excerpt from Vaccine Science Revisited: Are Childhood Immunizations As Safe As Claimed?:

The gut and the brain

“Within one linear centimeter of your lower colon there lives and works more bacteria (about 100 billion) than all humans who have ever been born. Yet many people continue to assert that it is we who are in charge of the world.” –Neil deGrasse Tyson (American astrophysicist)


Within the health sector, there has been much research done on communication between our enteric nervous system (ENS) and our central nervous system (CNS). An article in the Scientific American talks about a recent study on the relationship between the two.

The article states that:

“[…] scientists were shocked to learn that about 90 percent of the fibers in the primary visceral nerve, the vagus, carry information from the gut to the brain and not the other way around.”

The article continues on explaining the association between the two brains (the gut being the second brain) and disorders such as irritable bowel syndrome:

“[…] in fact 95 percent of the body's serotonin is found in the bowels. […]. Irritable bowel syndrome—which afflicts more than two million Americans—also arises in part from too much serotonin in our entrails, and could perhaps be regarded as a ‘mental illness’ of the second brain.”

When we hear statements like that, it’s not surprising to learn that irritable bowel syndrome (IBS) has been known to plague children with autism spectrum disorder (ASD). When it comes to diagnosis and how our view on the syndrome in general has evolved, the aforementioned paper states that:

“[w]hat was once viewed as an untreatable disease solely concerning the brain is now considered a dysfunction of the central nervous system (CNS) with accompanying disorders of the body in general as well as different organs/systems such as the immunological system or digestive tract.”

There have also been studies that show a correlation between ASD and pathogens in the colon and intestines. It may therefore not surprise you to know that children diagnosed with ASD experience positive changes in behavior when put on healthy food regimen.


The brain, stress and anxiety

There have been numerous studies confirming the correlation between autoimmunity and autism spectrum disorders (ASD). As many already know, children with ASD are sensitive to foods, so it shouldn’t come as a surprise that this autoimmunity often includes gluten antibodies, and milk antigens. Another antigen that may sound familiar and is a common one in this case, is the measles antigen. This antigen has also been known to affect proteins in the brains of children with ASD.

Celiac disease is an autoimmune disease in which the affected person is unable to digest gluten as gluten harms the small intestine. This disease turns out to be quite similar to autism. They both show brain injury related to food allergens like gluten. There have been more than 100 studies that have found correlation between these diseases and seizures, cranial nerve damage, dementia and impaired frontal lobe function.

A Harvard University researcher confirmed after a 2012 study the link between autism and inflammatory bowel disease.

In a 2015 article, he is quoted saying:

“From these population studies, larger than any to date, we find solid and reproducible evidence that the parents were right – as usual, […]. Based on the data I’ve seen, I suspect we will soon be able to define several distinct subtypes of ASD-associated bowel diseases.”

The most common neurological damage in autism is located in the cerebellum. We have cells in the cerebellum called Purkinje cells. Gluten antibodies have been seen to cross-react with these cells. In the brain of an individual with autism, most of the Purkinje cells are gone.

Children diagnosed with ASD have been found to usually have either relatives with allergies or their own personal history of allergies. Normally, people with these allergies have a negative skin or RAST test. This has led some scientist to believe ASD is related to “mast cell activation by non-allergic triggers.” It has been suggested one of those triggers may be mercury.

Vaccines have all types of antigens, not just from germs or toxins, but also food-related antigens. This triggers the microglia, which are cells in the brain and spinal cord, to become overstimulated.

Mast cells (MCs) can be found near neurons and microglia. They are believed to play an important role in giving molecules access to the brain. So, it comes as no surprise we have a vast number of mast cells near the blood-brain barrier (BBB).

When we are stressed, our hypothalamus secretes corticotropin-releasing factor (CRF). This factor works synergistically with neurotensin (NT), which regulates dopamine pathways. Together, they can aggravate the mast cells to the point of breaking the blood-brain barrier. Their synergistic reactions can cause the mast cells to cause brain fog and autism spectrum disorder (ASD). When the serum of children with ASD was tested, it was found to have elevated levels of both CRF and NT.

In this way, by weakening the blood-brain barrier, the mast cells (MC) have been shown to take part in the development of autism.

The role of corticotropin-releasing hormone (CRH) and neurotensin (NT) doesn’t stop there. CRH and NT are extremely sensitive to stress, so when the body is under a lot of stress they will activate the mast cells to promote an inflammatory process. Some scientists say this contributes to Chronic Fatigue Syndrome (CFS) and fibromyalgia.

This may seem farfetched, but anxiety and stress have been shown to be common in children with ME/CFS and as mentioned above, CFS can trigger inflammation that can affect the brain. This begs the question, which we have not attempted to answer in this book, whether high anxiety and stress can trigger brain dysfunctions.


ASIA

Interestingly enough, all the important mediators said to trigger ME/CFS can be traced to implicate the mast cells (MC), which are the cells near, among other places, our blood-brain barrier (BBB).

A syndrome that arose as a consequence of vaccination is the autoimmune syndrome induced by adjuvants (ASIA) . ME/CFS falls under the ASIA umbrella.

Another illness that falls under this umbrella is macrophagic myofasciitis (MF or MMF). The main symptom of this disease is that the macrophages gravitate around the injection site and are filled with aluminum hydroxide from the vaccines. This is called granuloma, which is the name for a cluster of macrophages that have gathered around the injected area and caused inflammation. This is known as Macrophagic (by macrophages) Myofasciitis (inflammation of muscle tissue).

A paper published in 2013 explains how researchers injected mice with aluminum to see what would happen. They noticed that the macrophages engulfed the metal particles, forming granulomas. These granulomas then started spreading to other organs, including the brain.

The reason it’s so difficult to eliminate the aluminum adjuvant captured by macrophages is because when a macrophage sees a foreign substance, it hugs the invader and pulls it inside. Once the invader is inside the cell membrane, the macrophage tears it into multiple tiny fragments. Some individuals don’t have the ability to eliminate the toxins, so instead it just accumulates inside their macrophages.

When presented with multiple vaccines simultaneously or in a short period of time, just about anybody can be the victim of overwhelmed macrophages. In most individuals, these granulomas become smaller with time and eventually disappear. But then you have the few individuals who, for some reason or other, have difficulties facilitating this process and it ends up having dire consequences.

Another disease that falls under the ASIA umbrella is the Gulf War Syndrome (GWS). You don’t have to have been anywhere near Kuwait or the Persian Gulf to be diagnosed with the GWS, although it’s normally isolated to those in the military since it was the anthrax vaccine that caused severe problems for military personnel in the Gulf War.

This book is focused on childhood vaccines, which does not include the anthrax vaccine, so we’ll make it quick. Many believe it was the squalene in the vaccine that was causing the GWS. The squalene is used instead of gelatin as many are allergic to that animal-product. Other vaccines that use squalene are some of the influenza vaccines. It’s perhaps worth noting that the anthrax vaccine contains aluminum and GWS is said to be very much like macrophagic myofasciitis (MMF).

References for Chapter 44: The gut and the brain:

Scientific American. (2010, February 12). Think Twice: How the Gut’s “Second Brain” Influences Mood and Well-Being. Retrieved from https://www.scientificamerican.com/ar...
Scientific American. (2010, February 12). Think Twice: How the Gut’s “Second Brain” Influences Mood and Well-Being. Retrieved from https://www.scientificamerican.com/ar...
Wasilewska, J. and Klukowski, M. (2015). Gastrointestinal symptoms and autism spectrum disorder: links and risks – a possible new overlap syndrome. Pediatric Health, Medicine and Therapeutics, 6, 153-166
Horvath, K., Papadimitriou, J.C., Rabsztyn, A., Drachenberg, C., and Tildon, J.T. (1999). Gastrointestinal abnormalities in children with autistic disorder. J Pediatr, 135(5), 559-563
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Mark wrote: "It’s all just a part of more and more “New Age” or previously “spiritual” ideas becoming more accepted due to time passing and more science having been done on them showing validity and reproducing the results...."

Interesting perspective.

James wrote: "Mark wrote: "It’s all just a part of more and more “New Age” or previously “spiritual” ideas becoming more accepted due to time passing and more science having been done on them showing validity an..."

The zodiac has always been considered pseudoscience yet I don’t see it going away anytime soon, and popularity doesn’t equate with truth, no matter how many people believe in it.

I think the “most serotonin gets made in the gut” fact is related to how the dimethyltryptamine molecule could be made in the lung. But, I think the food part is pushing it, as far as using it as an indication of ASD. Everyone reacts to food with dopamine, as the reward chemical, so it’s a pretty common thing that changes behavior. When you mix veganism with animal cruelty it makes it harder to eat dairy. I suspect the real problem is prevention rather than supplementing.

If it’s about this: https://en.m.wikipedia.org/wiki/Vagus...
thanks for the source. The internet is always a dodgy place to get sources, so it’s nice to at least have an edited book with useable information. If you’re just “randomly” googling stuff and using wiki and various webpages as sources, it can take a while to compile into a message you aim to give to an audience.