Brain-derived neurotrophic factor (BDNF) plays a pivotal role in neuronal survival, synaptic plasticity, and cognitive resilience during aging. Declining BDNF levels are strongly associated with age-related cognitive impairment and neurodegenerative disorders. Music therapy, a non-invasive intervention, has shown promise in enhancing neuroplasticity and modulating neurochemical signaling. However, the mechanisms linking music therapy to BDNF signaling in the aging brain remain underexplored. This systematic review aimed to examine the evidence on…
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Published on August 29, 2025 10:19